Opioid Use Disorder (OUD) is a complex medical condition that requires comprehensive care, combining medical treatment with counseling and support. At Sleep & Wellness Medical Associates, we are committed to offering innovative, effective treatment options—one of which is Sublocade injection.
In this guide, we will explain what Sublocade is, how it works, its benefits, potential side effects, and who might be eligible.

What is Sublocade?
Sublocade is an FDA-approved, once-monthly injectable form of buprenorphine, designed for adults with moderate to severe OUD who are already stabilized on oral buprenorphine. Unlike daily medications, Sublocade delivers a steady dose over 30 days, reducing cravings and withdrawal symptoms without the ups and downs of daily dosing.
For detailed medical information, you can review the official Sublocade Prescribing Information.
How Sublocade Injection Works
- Monthly administration: Given under the skin (subcutaneous) by a certified healthcare provider.
- Steady medication release: Maintains stable buprenorphine levels in the body.
- Blocks opioid effects: Reduces the rewarding sensation from opioid use, helping you stay on track.
This consistency can be life-changing for patients who struggle with daily medication adherence.
Key Benefits of Sublocade Injection
- Improved Treatment Success
Clinical studies show that patients receiving Sublocade with counseling were 14x more likely to stay opioid-free for most of their treatment period compared to placebo. - Convenience
With once-monthly dosing, there’s no need to remember daily pills—freeing up time for work, family, and recovery activities. - Reduced Relapse Risk
Steady medication levels reduce cravings and withdrawal symptoms, supporting long-term recovery. - Privacy and Discretion
No pill bottles or daily dosing means less stigma and greater confidentiality.
Potential Risks and Side Effects
Like all medications, Sublocade comes with risks.
Serious risks include:
- Breathing problems (especially with alcohol, benzodiazepines, or other depressants)
- Severe allergic reactions
- Liver damage
- Opioid withdrawal if injected improperly
Common side effects include:
- Constipation
- Nausea or vomiting
- Headache
- Injection site pain or itching
- Fatigue
Important: Sublocade is only available through a REMS (Risk Evaluation and Mitigation Strategy) program to ensure safe use.
Who is Eligible for Sublocade?
You may be eligible if you:
- Are an adult with moderate to severe OUD
- Have been on oral buprenorphine for at least 7 days
- Do not have severe liver or breathing problems
- Are not allergic to buprenorphine or other ingredients in Sublocade
Your provider will determine eligibility during a comprehensive evaluation.
Getting Started with Sublocade at Sleep & Wellness
At Sleep & Wellness Medical Associates, we take a compassionate, whole-patient approach:
- Initial Consultation: Discuss your history, current treatment, and goals.
- Insurance Verification: We check your coverage and explore assistance programs if needed.
- Monthly Injections: Administered in-office by trained professionals.
Ongoing Support: Counseling, lifestyle recommendations, and regular progress checks.
Why Choose Sleep & Wellness Medical Associates?
At Sleep & Wellness Medical Associates, we are dedicated to providing comprehensive, patient-centered care for individuals seeking improved health and quality of life. Located in Lawrence Township, NJ, our practice offers a wide range of services, from advanced sleep medicine and wellness programs to innovative treatments for addiction recovery, such as Sublocade for Opioid Use Disorder.
About Dr. Mahmood Siddique
Dr. Mahmood Siddique, DO, FACP, FCCP, FAASM, is a triple board-certified physician specializing in internal medicine, pulmonary medicine, and sleep medicine. With decades of clinical experience, Dr. Siddique is known for his compassionate approach, commitment to evidence-based care, and dedication to helping patients achieve long-term health and recovery. His leadership has made Sleep & Wellness a trusted destination for both preventive and specialized treatments.
Take the Next Step in Recovery
If you or a loved one is struggling with OUD, Sublocade injection could be a powerful step toward lasting recovery. Contact us today to schedule your consultation.
Frequently Asked Questions About Sublocade Injection
- What is Sublocade?
Sublocade is an FDA-approved, once-monthly injection of buprenorphine extended-release. It is used to treat moderate to severe opioid use disorder (OUD) in adults who are already stabilized on oral buprenorphine. - How is Sublocade given?
Sublocade is injected just under the skin in your abdomen by a certified healthcare provider. It slowly releases medication over one month, helping to reduce cravings and withdrawal symptoms. - How does Sublocade help with opioid addiction?
By providing a steady level of buprenorphine in your body, Sublocade reduces cravings, blocks the effects of opioids, and supports long-term recovery without the need for daily medication. - Who can receive Sublocade?
Adults diagnosed with moderate to severe OUD who have been taking oral buprenorphine for at least seven days may be eligible. Your doctor will evaluate your medical history and current health before recommending it.
Disclaimer: this article is for informational purposes only

